Hematological > B-NHL
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Area under investigation,AML/MDS,B-ALL,B-NHL=true,Classical Hodgkin lymphoma,CLL,DLBCL/LBCL,FL,MCL,Multiple myeloma
Tumor
R/R B-Cell ALL
Trial Identifier
NCT07109219
Phase
I/II
Regimen
AZD4512 monotherapy and in combination with other anticancer treatments
Relapsed/refractory multiple myeloma
NCT05850234
AZD0120 (GC012F)
Early line MM (including newly diagnosed MM and early relapsed or primary refractory MM)
NCT07073547
I
AZD0120
Relapsed/refractory MM
NCT06235229
Relapsed refractory multiple myeloma
NCT07391657
III
AZD0120; DKd, DPd, PVd or Kd (investigator’s choice) until PD or intolerable toxicity
Previously untreated non-GCB subtype DLBCL
NCT04529772
R-CHOP ± acalabrutinib
R/R B-NHL
NCT07123454
AZD4512 monotherapy or in combination with other anticancer treatments
AML/MDS with KMT2Ar, NPM1m, or other genotypes associated with HOX overexpression
NCT07155226
AZD3632 (module 1), AZD3632 + posaconazole (Module 2)
NCT04594642
Surovatamig
R/R multiple myeloma
NCT06106945
Vemzatatug vedotin
R/R classical Hodgkin lymphoma
NCT06137144
AZD3470 as monotherapy and in combination with anticancer agents
Relapsed/refractory B-cell NHL or FL and LBCL
NCT06526793
II
Surovatamig monotherapy
CLL/SLL with uIGHV
NCT07509151
Surovatamig consolidation therapy
Newly diagnosed LBCL
NCT07215585
Surovatamig; R-mini-CHOP
R/R CLL/SLL, MCL, and LBCL
NCT06564038
Sub-study 1 (RR CLL/SLL): surovatamig IV or SC; sub-study 2 (RR MCL): surovatamig IV or SC; sub-study 3 (RR LBCL): surovatamig IV + R-CHOP
Previously untreated follicular lymphoma
NCT06549595
Surovatamig + rituximab; SoC Immunochemotherapy
Relapsed/refractory B-cell acute lymphoblastic leukemia
NCT06137118
Relapsed/Refractory LBCL, FL, MCL, and CLL
NCT06542250
AZD5492 monotherapy